Anti-Galectin-3

Analysis Note

ControlMG-63 cell lysate

Application

Research CategoryApoptosis & Cancer

Research Sub CategoryApoptosis - Additional

This Anti-Galectin-3 Antibody is validated for use in WB for the detection of Galectin-3.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

General description

Galectin-3 belongs to the galectin gene family, which is defined by the specificity of a carbohydrate recognition domain (CRD) for Gal/Lac. Galectin-3 expression is usually elevated in a wide range of neoplastic cell types. The galectin CRD consists of 135 amino acids. Galectin-3 is known to play a role in tumor development, apoptosis, and cell cycle progression.

Immunogen

KLH-conjugated linear peptide corresponding to the Pro64 mutation domain of human Galectin-3.

Epitope: Pro64 mutation domain

Physical form

Affinity purified

Purified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.

Quality

Evaluated by Western Blot in MG-63 cell lysate.

Western Blot Analysis: A 1:250 dilution of this antibody detected Galectin-3 in 10 µg of MG-63 cell lysate.

Specificity

This antibody recognizes the Pro64 mutation domain of Galectin-3. It is equally specific for wild-type or mutant His64 Galectin-3.

Storage and Stability

Stable for 1 year at 2-8°C from date of receipt.

Target description

~33 kDa observed