ANTI-FASLG ANTIBODY PRODUCED IN RABBIT

Code: SAB5700609-100UL D2-231

General description

This gene is a member of the tumor necrosis factor superfamily. The primary function of the encoded transmembrane protein is the induction of apoptosis tr...


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General description

This gene is a member of the tumor necrosis factor superfamily. The primary function of the encoded transmembrane protein is the induction of apoptosis triggered by binding to FAS. The FAS/FASLG signaling pathway is essential for immune system regulation, including activation-induced cell death (AICD) of T cells and cytotoxic T lymphocyte induced cell death. It has also been implicated in the progression of several cancers. Defects in this gene may be related to some cases of systemic lupus erythematosus (SLE). Alternatively spliced transcript variants have been described.

Immunogen

A synthetic peptide corresponding to a sequence within amino acids 100-200 of human FasLG (NP_000630.1).

Physical form

PBS with 0.02% sodium azide,50% glycerol,pH7.3.

Storage and Stability

Store at -20℃. Avoid freeze / thaw cycles.

antibody formaffinity isolated antibody
antibody product typeprimary antibodies
biological sourcerabbit
clonepolyclonal
concentration1.52 mg/ml
formbuffered aqueous solution
Gene Informationhuman ... FasLG(356)
mol wt31, 14
Quality Level100
shipped inwet ice
species reactivityrat, mouse, human
storage temp.−20°C
technique(s)western blot: 1:500-1:2000
UniProt accession no.P48023
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