Biochem/physiol Actions

Cell permeable: no

Reversible: no

Primary TargetActivator of AMPK (AMP-activated protein kinase)

Product does not compete with ATP.

General description

A 5′-phosphorylated analog of membrane permeable AICA-Riboside (Cat. No. 123040) that mimics AMP and acts as an activator of AMPK (AMP-activated protein kinase).

A 5′-phosphorylated analog of membrane permeable AICA-Riboside (Cat. No. 123040) that mimics AMP and acts as an activator of AMPK (AMP-activated protein kinase).

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Other Notes

Fryer, L.G.D., et al. 2002. Biochem. J.363, 167.Henin, N., et al. 1996. Biochim. Biophys. Acta1290, 197.Corton, J.M., et al. 1995. Eur. J. Biochem.229, 558.Sullivan, J.E., et al. 1994. Biochem. Biophys. Res. Commun.200, 1551.Sabina, R.L., et al. 1985. J. Biol. Chem.260, 6107.

Packaging

25 mg in Glass bottle

Packaged under inert gas

Preparation Note

Only water soluble following extensive heating.

Reconstitution

Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.

Warning

Toxicity: Standard Handling (A)